ransepidermal elimination is a disorder in which T dermal stimuli profoundly effect the behavior and structure of the overlying epidermis. Briefly, there are two categories of disorders: the first are primary dermatoses and consist of elastosis perforans serpiginosa and reactive perforating collagenosis; the second group originates from alterations of dermal constituents in preexisting disorder...

BACKGROUND Few studies have focussed on the transepidermal elimination of parasites in Jorge Lobo's disease (lobomycosis). OBJECTIVE To identify the morphological features of the transepidermal elimination of parasites in lobomycosis. METHODS Sections were obtained from paraffin-embedded biopsy specimens of patients with lobomycosis and stained with hematoxylin-eosin for microscopic examina...

Perforating dermatoses (PD) represent a rare group of papulonodular skin diseases with a distinct central keratotic core. The core represents the transepidermal elimination of an altered dermal substance.1 Diagnosis is established via biopsy and histopathologic evaluation. Whereas primary PD are diseases chiefly characterized by transepidermal elimination, secondary PD are a group of unrelated ...

Transepidermal elimination (TE) is a mechanism whereby foreign or altered constituents can be removed from the dermis. This process involves unique morphologic alterations of the epidermis, which forms a channel and thereby facilitates extrusion of the desired dermal components. The phenomenon of TE may occur as a primary process characterizing disorders, such as elastosis perforans serpiginosa...

We report the case of a 49-year-old male with clinical and histological findings consistent with hypertrophic lupus erythematosus (HLE). HLE must be clinically and histologically differentiated from keratoacanthoma, hypertrophic lichen planus, squamous cell carcinoma and plaque type psoriasis. CD123 positivity and transepidermal elimination of elastin have recently been reported as tools to dis...